About 1 result found for searched term "ZINC05007751 " (0.138 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30332 | ZINC05007751 | Others |
| ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM. ZINC05007751 shows antiproliferative activity against a panel of human cancer cell lines, and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity was observed against NEK2, NEK7, and NEK9. | ||
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